Getting rid of the bed bugs in your bed is not so difficult. However, this won't help if you have them around your home. You will need to clean your home and spray for the bug. They can also get in your furniture, carpet, clothes, towels, and pillows.
Buying a plastic mattress cover is the first step to killing the bugs in your mattress. Now you need to take all of your bedding and wash it at the highest temperature on your wash cycle and then dry the clothes in the hottest setting on your dryer. Once this is done bag all the items up in plastic bags and seal them until you are done cleaning the rest of your home.
You will need to do this with all your clothes in your home and this includes your spare sheets, blankets, and towels. If you don't kill the bugs in your home they will continue to multiply and come back. Now you'll need to clean your rugs and furniture. You will need to pull back the rug from the wall and spray for the bugs along the baseboard of your home and the rug. If you have fabric on your furniture this will need to be sprayed too. You'll also need to check your books and everything in your home to make sure you don't have bugs in there.
If you live in an apartment the bugs more than likely came into your home from a neighbor. You'll need to report this to the landlord so he can have the other apartment sprayed in your complex.