The answer is yes, frustration and hypertension can be interrelated. When someone feels frustrated, their stress levels tend to rise, leading to increased blood pressure and hypertension. The adrenaline that is released when someone experiences a lot of stress can constrict blood vessels and increase blood pressure, causing the heart to pump harder and more forcefully. Over time, this can cause hypertension, especially if the person is already predisposed to it or already has risk factors like high cholesterol, obesity, or diabetes. The best way to avoid this situation is to be aware of stress levels and find ways to cope with and reduce them, as well as exercising regularly and eating a healthy diet.