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What are GMP Lentiviral Vectors? How are lentiviral vectors made? What is the use of lentiviral vectors in gene therapy?

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Lentiviral vectors are made by inserting genetic material into a lentivirus, which is a type of retrovirus. The genetic material is then packaged into a viral particle and used to deliver genes to target cells. Lentiviral vectors are used in gene therapy to insert a functional gene into cells, which can be used to treat genetic diseases. Lentiviral vectors can also be used to deliver genes to cells for research purposes. GMP (Good Manufacturing Practice) Lentiviral Vectors are lentiviral vectors that have been produced in a controlled environment according to GMP standards.
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Lentiviral vectors are made by combining three different viruses: a lentivirus, a gag virus, and a vesicular stomatitis virus (VSV).

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The production of lentiviral vectors centers around the use of a cell line, typically referred to as a packaging cell, to produce the viral vector particles. Large-scale manufacturing of vectors begins with the growth of an adequate number of these packaging cells
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