Of course! No matter how good your business is, if it's not in a strategic place, for sure it will go bankrupt. Before putting up a business, you should first know your consumers, profile them, what would appeal to them and what would not, where do they hang out, stuff like that. Let's take for example a 7/11 convenience store. We all know that it is one of the largest earning convenience stores especially in the cities. However, if we put a 7/11 store in a place where no one really stays up later than say 9pm, and where there are a lot of small stores whose prices are not as jacked up as in 7/11, then that 7/11 outlet would just go to waste especially since 7/11 is open 24 hrs. Just think about the wasted money on electricity and labor for that time (9pm to maybe 6am) when no one even comes in to buy something because everyone is still asleep.