As of my last knowledge update in January 2022, I don't have access to real-time information or restaurant reviews. The best South Indian restaurant in Harrisburg, PA, can change over time, so I recommend checking recent reviews and restaurant listings on platforms like Yelp, Google Maps, or TripAdvisor to find the most up-to-date information on South Indian restaurants in the area. Reading reviews and asking locals for recommendations can help you discover the top South Indian dining options in Harrisburg.