Andy Murray's first Grand Slam title was at the 2012 US Open. He defeated Novak Djokovic in five sets, winning the championship 7-6(10), 7-5, 2-6, 3-6, 6-2. Murray became the first British man to win a Grand Slam singles title in 76 years. His victory at the US Open marked a significant milestone in his career, as he had previously finished runner-up in four Grand Slam finals.