Lisa Simpson, the intelligent and socially conscious daughter of the Simpson family, was inspired by a real-life person. The character of Lisa Simpson was partly inspired by the creator of "The Simpsons," Matt Groening's sister, Lisa Groening. Lisa Groening is an accomplished author and environmentalist who shares some similarities with the character Lisa Simpson, such as their intelligence and passion for various causes. However, it's important to note that while Lisa Simpson was inspired by Lisa Groening, the character is a fictional creation and has developed into a unique and beloved character in her own right.