The Bryan brothers, Bob and Mike, hold the record for the most ATP Masters 1000 tournament doubles titles. They won a total of 39 titles, which is more than double the number of titles won by the second-highest pair on the list. The brothers have also won multiple grand slam titles, including the US Open, Wimbledon, and the Australian Open. They retired from professional tennis in 2020, after an illustrious career that spanned over two decades.