it depends mainly on two things, the product you will be using, where you will be injecting in, how much you will be injecting and the speed at which the body metabolize the filler material. we found that some can last from 6 months to a year and others from 2 to 5 years. for example Juvederm Vollure can last up to 18 months, Sculptra can last up to 24 months, while the most effective in terms of duration is Bellafill which can last to 5 years.