The catchphrase "What you talkin' 'bout, Willis?" was famously spoken by actor Gary Coleman on the American television show "Diff'rent Strokes." "Diff'rent Strokes" aired from 1978 to 1986 and followed the lives of two African-American brothers, Arnold (played by Gary Coleman) and Willis Jackson (played by Todd Bridges), who are adopted by a wealthy white man named Mr. Drummond. Gary Coleman's portrayal of Arnold and his delivery of the catchphrase became iconic, and the show gained popularity during its run.