Filtration: The kidneys act as filters, receiving blood from the renal arteries. They selectively filter waste products, excess water, and electrolytes from the blood to form a fluid called filtrate. Filtration occurs in tiny structures within the kidneys called nephrons.
Reabsorption: As the filtrate passes through the nephron, essential substances such as water, glucose, amino acids, and electrolytes (sodium, potassium, chloride, etc.) are selectively reabsorbed back into the bloodstream. The extent of reabsorption depends on the body's needs and the concentrations of these substances in the blood.
Secretion: While reabsorption returns necessary substances to the bloodstream, secretion involves actively moving additional waste products and excess ions from the bloodstream into the nephron. This process helps regulate the concentrations of substances like hydrogen ions, potassium, and drugs or toxins in the body.
Concentration and Dilution: The kidneys have the ability to concentrate or dilute urine depending on the body's hydration needs. This process occurs in the loop of Henle, a part of the nephron. By reabsorbing water and electrolytes back into the bloodstream or allowing their excretion, the kidneys can adjust the concentration of urine to maintain water and electrolyte balance.
Hormonal Regulation: Several hormones play a role in water and electrolyte balance regulation. For example, antidiuretic hormone (ADH), produced by the pituitary gland, promotes water reabsorption in the kidneys, reducing urine volume. Aldosterone, produced by the adrenal glands, regulates the reabsorption of sodium and water, which affects blood volume and electrolyte balance.
Acid-Base Balance: The urinary system also contributes to maintaining the body's acid-base balance. The kidneys help regulate the levels of hydrogen ions (acidity) and bicarbonate ions (alkalinity) in the blood by excreting excess acids or bases into the urine or reabsorbing bicarbonate ions as needed.