QWO stands for "Collagenase clostridium histolyticum-aaes (Qwo)," which is a prescription medication used in the treatment of cellulite in the buttocks of adult women. It is a type of injectable treatment that works by breaking down the tough fibrous bands that contribute to the appearance of cellulite, thereby improving the skin's texture and appearance. QWO is a brand name, and the active ingredient, collagenase clostridium histolyticum, is a type of enzyme that specifically targets the fibrous bands that cause cellulite.